每天攝入6包速溶咖啡（15g）+3罐紅牛（250ml），長期下去會對身體造成怎麼樣的影響？

01-18

男，27歲

我不知道任何臨床上飲用咖啡因飲料致死的案例。參考大鼠的半致死劑量260mg/kg，一個70kg的成人要在有限時間內攝入18.2g咖啡因，相當於227罐半紅牛——Caffeine in Red Bull。前面兩位言之鑿鑿回答會致死的老師，請指正謝謝。

對於成人，Health Canada給出的每日建議量是400mg，大概是5罐紅牛的量，題主給出的基本不出意外超過這個數值了。過量的咖啡因會引起過度亢奮，焦躁、緊張、心動過速什麼的。咖啡因在體內代謝很快，沒有證據會累積毒性。但是長期過量的話身體會產生對咖啡因的適應，中斷的時候會產生一些不良反應。

升天，坐在羅豆的右邊。

會長胖

紅牛的主要問題是苯甲酸鈉，小酌無妨，牛飲傷腎；咖啡因攝入過多會造成心腦血管負擔，且影響睡眠時間和質量。以前複習的時候，兩種同時喝了兩個月左右，結果就是考完停用後很長一段時間內，一到晚八九點，腦子就自動罷工，什麼都幹不了，必須睡十二小時左右才能感覺正常，且期間不會做夢。

這事邀請我？我已經好久不豁命了。

ace zh已經回答很詳細了數據化的東西。

說一些身邊的人和事，美帝同事。每天3杯咖啡以上，必須喝。不喝整個人開會注意力完全不集中。美式不加任何東西，嚴重性咖啡因依賴。不喝的話脾氣各種暴躁，各種和丫吵架。有段時間夏天犯困，下午自己煮咖啡。發現過段時間不喝整個下午沒發集中精力，犯困睡不著。各種浮躁，上火。後來改睡午覺，睡個20分鐘內都比喝咖啡強。

咖啡＋紅牛我能想到後果就是上火，各種上火。整個人興奮狀態就會變成亢奮狀態了，單獨處理一件事情會很好（比如編程，寫作……）但是要是處理交叉工作或者碎片化工作就會讓自己變得狂躁容易發脾氣，而不能注意力集中處理事情。

長期下去會導致不服用就會萎靡不振，因為自身免疫系統不會再為你提供任何興奮和保持活力的激素了。這有點類似於長期經常服用漱口液的人，如果不用會口臭（我說的是那種每天抱著漱口液，沒事就漱口的人。不是一天早晚正常使用的。註：真的服了知乎咬文嚼字的主兒，啥事都得說圓滿了）

還是建議運動前和這類東西比較好，或者是自身本來處於新陳代謝高的時候（運動、健身這類）

攝入咖啡因的劑量為200-750mg能引起的不良癥狀包括噁心，頭痛，和心律不齊，

攝入咖啡因的劑量為750-1000mg能引起嚴重的毒性癥狀。嚴重咖啡因中毒可導致噁心，嘔吐，焦慮，震顫，抽搐，心動過速，心律失常，低血壓，低血鉀和代謝性酸中毒。

按照 @ace zh的答案里所說的就是1罐紅牛相當於0.08g咖啡因，3罐也就是0.24g咖啡因

速溶咖啡的標準

Show Foods

3包15g速溶咖啡就相當於0.47g咖啡因

那一天咖啡因的攝入量就達到了0.71g咖啡因

按照上述標準：

攝入咖啡因的劑量為200-750mg能引起的不良癥狀包括噁心，頭痛，和心律不齊

當然了，這只是一天的攝入量即會如此，天天這樣的話那就未知了。

咖啡因過量導致死亡已有被記錄在案，但相對來說還是極為罕見的。在大量攝入咖啡因情況下，其引發的嘔吐常常可防止致命性中毒，但依舊導致了一些人死亡。咖啡因人類致死劑量範圍被認為是3-20g，大約就是20-130杯滴漏式咖啡或15-100片咖啡因片（200mg/p）(範圍較大）。血液中咖啡因含量大於80ug/ml即能致死，但相關數據並不多。一般人很難一次攝入這麼高水平的咖啡因，大部分致死記錄中死者的動機是企圖通過大量口服咖啡因片自殺。但也有達到致死量卻未死的案例，一個極端的例子，一名41歲的女子在攝入50g咖啡因後依舊被救活。以下是案例，有過量致死的也有未致死的。

Incident: Stiner J, 18. May 27, 2014 #

Logan Stiner, 18 years old, was found unresponsive by his brother at home after ingesting an unknown amount of pure caffeine powder, possibly mixed into a drink.
Editors. "High School Senior Dies After Ingesting Toxic Amount Of Caffeine Powder". CBS Cleveland. June 30, 2014.LAGRANGE, Ohio (CBS Cleveland) A senior at Keystone High School was found dead after he ingested toxic amounts of caffeine powder. WJW reports that Logan Stiner, 18, was found unresponsive by his brother in their family home. Steven Evans, the Loraine County Coroner told the station that Stiner death was a result of having toxic levels of caffeine in his blood after ingesting the powder. The overdose caused cardiac arrhythmia and a seizure.[...] Evans said that Stiner was alone when he ingested the powder, so it is not known how much he drank.
Reid M. School reeling from sudden death of stand-out senior. Fox 8 Cleveland. May 28, 2014.LAGRANGE, Ohio A community is reeling from the death of a high school senior just days before graduation. The halls were quiet at Keystone High School in LaGrange Wednesday. "Usually at this time of year, there is joy and anticipation. I didn"t see any of that today," said teacher Phil Tuttle. That because students and the community are mourning the death of Logan Stiner, 18, who died of natural causes at home Tuesday.

Alstott RL, Miller AJ, Forney RB. Report of a human fatality due to caffeine. J Forensic Sci. 1973;18(2):135-7. [ Abstract ]
An individual (age unknown) died after consuming between 6.5 and 12 g caffeine.

Garriott JC, Simmons LM, Poklis A, Mackell MA. Five cases of fatal overdose from caffeine-containing "look-alike" drugs. J Anal Toxicol, 1985; 9(3):141-3. [ Abstract ]
Mixed ephedrine and caffeine fatalities, showed blood levels of 130-344 mg/L caffeine and three also had 3.5-20.5 mg/L of ephedrine.

Holmgren P, Norden-Pettersson L, Ahlner J. Caffeine fatalities--four case reports. Forensic Sci Int, 2004; 139(1):71-3 [ Abstract ]
Four cases reported: 54 yr old male died after taking 100 x 100 mg caffeine tablets resulting in 173 mg/L in femoral blood. 21 yr old male died after ingesting 200 x 100 mg caffeine tablets resulting in 210 mg/L in femoral blood. 31 yr old male died after ingesting 100 x 100 mg tablets resulting in 153 mg/L in blood sample. 47 yr old female died after ingesting 100 tablets containing both caffeine and ephedrine resulting in 200 mg/L of caffeine and 4.8 mg/L of ephedrine.

Kerrigan S, Lindsey T. Fatal caffeine overdose: two case reports. Forensic Sci Int, 2005; 153(1):67-9 [ Abstract ]

39 yr old female found dead with 192/mgL caffeine in femoral blood. 29 yr old male had taken "a bottle of caffeine pills the day before" died while in hospital and had 567 mg / L caffeine in femoral blood.

McGee MB. Caffeine poisoning in a 19-year-old female. J Forensic Sci. 1980 Jan;25(1):29-32. [ Abstract ]
19 yr old female died after ingesting over the counter appetite suppresant. Dose unknown.

Mrvos RM, Reilly PE, Dean BS, Krenzelok EP. Massive caffeine ingestion resulting in death. Vet Hum Toxicol. 1989 Dec;31(6):571-2. [ Abstract ]
22 yr old female died after ingesting diet pills. Highest known blood levels 1,560 mg/L.

Shum S, Seale C, Hathaway D, Chucovich V, Beard D. Acute caffeine ingestion fatalities: management issues. Vet Hum Toxicol. 1997;39(4):228-30 [ Abstract ]
A 32 yr old female experienced multiple seizures and fatal cardiac arrest after ingesting 20 g caffeine. A 15 yr old female suffered seizures and fatal cardiac arrest after ingesting 80 caffeine tablets of unknown strength.

Walsh I, Wasserman GS, Mestad P, Lanman RC. Near-fatal caffeine intoxication treated with peritoneal dialysis. Pediatr Emerg Care. 1987 Dec;3(4):244-9. [ Abstract ]
2 yr old female died after orally ingesting caffeine.

Winek CL, Wahba WW, Winek CL Jr, Balzer TW. Drug and chemical blood-level data 2001. Forensic Sci Int, 2001; 122(2-3):107-23 [ Abstract ]

No citation is given, but Winek et al."s comprehensive therapeutic and toxic blood level data is considered a good source. Winek et al. give "> 100 ug/ml" as the "Lethal" level for caffeine. That works out to 100 mg/L.

Non-Fatalities

Dietrich AM, Mortensen ME. Presentation and management of an acute caffeine overdose. Pediatr Emerg Care. 1990 Dec;6(4):296-8. [ Abstract ]
Non-Fatal. 1 yr old female ingested 2-3 grams caffeine (200-300 mg/kg), showed blood levels of 385 mg/L and survived with hospital care.（搶救活了）

Forman J, Aizer A, Young CR. Myocardial infarction resulting from caffeine overdose in an anorectic woman. Ann Emerg Med. 1997 Jan;29(1):178-80. [ Abstract ]
Non-Fatal. 20 yr old bulimic woman ingested 20g caffeine, did not die but suffered subendocardial infarction.（但最後還是心肌梗死）

Holstege CP, Hunter Y, Baer AB, Savory J, Bruns DE, Boyd JC. Massive caffeine overdose requiring vasopressin infusion and hemodialysis. J Toxicol Clin Toxicol. 2003;41(7):1003-7. [ Abstract]

Leson CL, McGuigan MA, Bryson SM. Caffeine overdose in an adolescent male. J Toxicol Clin Toxicol. 1988;26(5-6):407-15. [ Abstract ]
Non-Fatal. 16 yr old male ingested estimated 6-8grams caffeine and survived with hospital care.（搶救活了）

來源：Erowid Caffeine Vaults : Health : Overdoses Deaths

速溶別喝了，裡面的香精和其他的添加劑比咖啡因更折騰人。而且速溶用的都不是什麼好咖啡豆子，質量最差的羅布斯塔豆子一般都是拿去做速溶的，生豆裡面甚至混著石頭，進廠第一件事就是篩石頭。。。蟲蛀豆發霉豆壞豆就不說了，至少有20%以上的瑕疵率。這樣的破玩意直接深度烘焙完粉碎萃取。口味可想而知。速溶咖啡的味道基本是依靠香精

原來大家學咖啡的時候

一個上午喝了二十杯左右的濃縮

單份

然後下午開了心悸，感覺很嗨，和拉肚子

很嗨

(???_????)

然後現在有點上癮

一天3杯左右的單份濃縮

親測會長胖……

每天4袋速溶，1罐原味咖啡……持續了一學期，今天才恍然發覺自己胖……

決定戒了……

可是，覺得好難呢……

只要不是混在一起喝，都沒問題。

都在關心咖啡因。有沒有人來說說牛磺酸？

您會活力無限，魅力四射！！！！

天天喝肯定不行，偶爾一兩天沒事的人